Forxiga is a brand name for the medication dapagliflozin. It belongs to a class of drugs called sodium-glucose cotransporter 2 (SGLT2) inhibitors. Forxiga is primarily used to treat type 2 diabetes mellitus, but it also has other therapeutic uses.
Here are some key points about Forxiga:
- Diabetes Treatment: Forxiga works by inhibiting the SGLT2 protein in the kidneys, which helps to lower blood sugar levels by increasing the amount of glucose excreted in the urine. This mechanism of action is independent of insulin secretion or action, making it useful for people with type 2 diabetes who may not adequately respond to other medications.
- Blood Sugar Control: By lowering blood sugar levels, Forxiga can help improve glycemic control in people with type 2 diabetes, reducing the risk of complications associated with high blood sugar levels, such as kidney damage, nerve damage, and cardiovascular disease.
- Cardiovascular Benefits: In addition to its glucose-lowering effects, Forxiga has been shown to have cardiovascular benefits. Clinical studies have demonstrated reductions in the risk of cardiovascular events such as heart attack, stroke, and cardiovascular death in people with type 2 diabetes who take Forxiga.
- Other Uses: Forxiga may also be prescribed off-label for other conditions, such as heart failure with reduced ejection fraction (HFrEF), as it has been shown to improve symptoms and reduce the risk of hospitalization for heart failure in some patients.
- Side Effects: Common side effects of Forxiga may include urinary tract infections, genital yeast infections, increased urination, and dehydration. Rare but serious side effects may include ketoacidosis (a serious complication of diabetes characterized by high levels of ketones in the blood) and acute kidney injury.
As with any medication, it’s essential to take Forxiga exactly as prescribed by a healthcare professional and to discuss any potential risks or side effects with your doctor before starting treatment.
