Liraglutide: Uses, Benefits, and Side Effects
Liraglutide is a prescription medication commonly used to manage type 2 diabetes, support weight loss, and reduce the risk of cardiovascular events. Marketed under brand names such as Victoza® (for diabetes) and Saxenda® (for weight management), liraglutide is a GLP-1 receptor agonist that mimics the action of the body’s natural incretin hormones.
How Liraglutide Works
Liraglutide works by:
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Enhancing insulin secretion in response to meals
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Slowing gastric emptying
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Reducing appetite and food intake
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Lowering blood glucose levels
These actions help improve glycemic control and support weight loss when combined with diet and exercise.
Indications
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Type 2 Diabetes: As an adjunct to diet and exercise for adults and children over 10 years old.
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Chronic Weight Management: For adults with a BMI ≥30, or ≥27 with weight-related conditions (e.g., hypertension, dyslipidemia, or type 2 diabetes).
Benefits
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Improved blood sugar control
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Significant weight reduction
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Decreased risk of heart attack, stroke, or cardiovascular death in adults with type 2 diabetes and established heart disease
Common Side Effects
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Nausea
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Vomiting
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Diarrhea or constipation
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Headache
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Low blood sugar (when used with other antidiabetic drugs)
Rare but serious side effects include pancreatitis, gallbladder disease, and potential thyroid tumors.
Important Safety Information
Liraglutide is not recommended for people with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Always consult your healthcare provider before starting treatment.